The antibiotic “Nafithromycin” has been developed with the support of “Biotechnology Industry Research Assistance Council” (BIRAC), a unit of the Department of Biotechnology and has been brought to market under the trade name “Miqnaf” by pharma company “Wolkardt”. It is the country’s first indigenously developed antibiotic aimed at tackling Antimicrobial Resistance (AMR).
The development of Nafithromycin represents 14 years of dedicated research and an investment of ₹500 crores, with clinical trials spanning the U.S., Europe, and India. It is Supported by BIRAC under its Biotechnology Industry Partnership Program (BIPP).
This innovation is designed to treat Community-Acquired Bacterial Pneumonia (CABP), a severe illness caused by drug-resistant bacteria, which disproportionately affects vulnerable populations, including children and the elderly as well as immune compromised hosts like Patients with Diabetes, Cancers etc.
Dr. Jitendra Singh described the three-day treatment regimen of Nafithromycin as a game-changer in addressing drug-resistant pneumonia, a condition responsible for over two million deaths globally each year. India, which bears 23% of the world’s community pneumonia burden, faces challenges with existing treatments, including widespread resistance to drugs like azithromycin. The new antibiotic, developed by Wockhardt with support from the Biotechnology Industry Research Assistance Council (BIRAC), is ten times more effective than current options and offers a safer, faster, and more tolerable solution for patients.
