Author: Biotech Express

Introduction The exome is the sum of all regions in the genome comprised of exons. The term exon was derived from “EXpressed regiON,” since these are the regions that get translated, as opposed to the intron, or “INTRagenic regiON” which is not represented in the final protein. Exome sequencing is a capture based method developed to identify variants in the coding region of genes that havea wide range of applications, including population genetics, genetic disease, and cancer studies. In 2001 human genome project required more than 200 scientists working for more than a decade with almost $3 billion cost while…

by Ramachandra Dilip, Sri Shakti Institute of Engineering and Technology (SIET), Coimbatore, India. ABSTRACT Tardigrade also known as water bear are one of the extremophiles which are said to have survived five mass extinction events. This tardigrades species are so stress tolerant that it can survive the vacuum of space, high and low temperatures, and strong doses of ionizing radiations. Ramazzotius varieornatus is one of tardigrade species, which have the genome size of 75 to 800 mbp of DNA, revealed to have about 19000 proteins.The genome is protected by a protein called DSUP, is one kind of a protein found…

“I will not be able to complete my graduate studies, I am very dumb”, a sad and gloomy face of my lab mate popped up as I saw her rising across from her chair. “I even don’t comprehend the fundamentals of my work and my “simple” experiments fail miserably” continued the explanation. There was sense of dejection as the fear of her PhD work rose over her. “You have lots of data and you are going good in PhD” my voice rose as I saw clear signs of despondency on her face. If this sounds usual to you, probably you…

It has been 5 years since Biotech Express was started with a notion to unite scattered Biotech academia and industry when there was no source of Indian news and information for academicians, scientists and industrialists. In August 2013 the first issue of Biotech Express was released and at that time our main focus was entirely to cover Academia and research of Biotech, so we started with the very basic topic of Model organisms in Biological research because no experiment can be completed without having starter culture. So in 12 issues we covered model organisms from smallest to largest which are…

The 4th Edition of International Conference on Plant Genetics and Genomics “Next Gen Crops for Sustainable Agriculture” was organized on July 19-20, 2018 in the Hotel Hometel, Chandigarh, India in which about 135 Scientists participated. This grand two days event witnessed around 27 enlightening Invited Talks, 5 Oral Presentations, 51 Poster Presentations and an Exhibition featuring Technology Giant like Merck Life Sciences. During the Welcome Address of the Conference, Dr Sanjay Bajaj, Managing Director, Select Biosciences India greeted all the Speakers, Delegates and Exhibitors while introducing the organization and its activities to the audience. This was followed by Speaker Introduction…

Professor Ashok Pandey is currently Distinguished Scientist at the Centre for Innovation and Translational Research, CSIR-Indian Institute of Toxicology Research, Lucknow, India and Executive Director (Honorary) at the Centre for Energy and Environmental Sustainability – India. Formerly, he was Eminent Scientist at the Center of Innovative and Applied Bioprocessing, Mohali and Chief Scientist & Head of Biotechnology Division and Centre for Biofuels at CSIR’s National Institute for Interdisciplinary Science and Technology, Trivandrum. His major research and technological development interests are industrial & environmental biotechnology and energy biosciences, focusing on biomass to biofuels & chemicals, waste to wealth & energy, industrial…

Introduction Long-term undifferentiated cell culture systems derived from inner cell mass of developing embryos are called as embryonic stern (ES) cell culture systems (Evans and Kaufman, 1981; Martin, 1981). These cells are pluripotent in nature and can be induced to differentiate into cells of different lineage. Which is found in multicellular organisms. Stem cells manly divide into two broad category, embryonic stem cells, which are isolated from the inner cell mass of blastocysts, and second is adult stem cells, which are found in several tissues. In adult animals, stem cells and precursor cells act as a repair system for the…

Introduction Man is the most evolved animal on earth and thus could be considered as the fittest living being nature has ever produced. Using the vast knowledge that nature has endowed him with, man has further shored his own defenses by an impressive range of weaponry. Yet, sadly all his ammunitions fails when it comes to defending his own body against the multitude of invisible, microscopic, disease causing organisms and molecules that surrounds him (Phondke, 1992). We are floating in an ocean of enemies of cunning microbes along with some deadly other factors such as automobile exhaust, radiation, cigarette smoke,…

Nipah Visrus has emerged as a deadly pathogen for South Asian countries and poses great threat if transmitted from one region to another. CDC and WHO have issued various guidelines and research grant schemes to combat deadly disease and to prevent its transmission into other parts of world. The disease has claimed 100s of life alone in Bangladesh and India after it was first reported in 1999. Though it seems that it has taken few lives but if ignored it can turn this earth into graveyard. In this article every aspect has been included to understand this deadly virus and…

Introduction From the very beginning of Science career, we are made of aware of IIT-JEE and Medical entrance exams (now NEET), and several among us get admission in coaching classes, even fromClass V/ VII; so we see people get really serious when career is concerned. And the moment we think of coaching classes, a city called Kota in Rajasthan comes to our mind. It has become a hub for producing future Engineers and Doctors. This development led to the development of Kota, generating employment/self-employment to thousands of people through shops, restaurants, hostels, etc. by Piyush Kumar, PhD