Author: Biotech Express

Nabanita Das, PhD Email: dasnabanita123@gmail.com SERB-National Postdoctoral fellow, CSIR-Central Drug Research Institute, Sector-10, Jankipuram extension, Sitapur Road, Lucknow-22603, Uttar Pradesh. India. Abstract Development of a brand new drug takes enormous toll on time, money and effort, due to bottlenecks in therapeutic development. Strategically repurposing drugs for other uses can save time and money, as their pharmacology, formulation and potential toxicity are already known. The preclinical phase includes a demonstration of its efficacy in invitro or in vivo model system and then filing the experimental new drug application with the U.S. Food and Drug Administration (FDA), it typically enters into clinical…

Covaxin has received Good Manufacturing Practices (GMP) compliance certificate from The National Institute of Pharmacy and Nutrition (OGYÉI), Hungary, the vaccine maker said on Thursday in a tweet. The National Institute of Pharmacy and Nutrition (OGYÉI) is appointed by the Government Decree as a licensing authority for pharmaceutical and public administrational matters. The main activity of OGYÉI is to provide the public with safe, effective and quality medicines in accordance with the regulations. OGYÉI is the national organization of official drug controlling tasks and it is also the methodical and research institute of Hungary. With this approval, Bharat Biotech achieved…

Republican Senator, an ophthalmologist and member of the Senate Health Committee Rand Paul confronted with Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases (NIAID) and the chief medical advisor to the president alleging that coronavirus gain of function research was funded by NIH during a testimony before a Senate on July 20, 2021. He also suggested that Fauci and the NIH could be partly responsible for the pandemic and the deaths of 4 million people worldwide. Paul allege that Fauci helped fund research and lied to Congress while under oath about Gain of Function research, he…

The Indian company Bharat Biotech (BB) on 3rd July 2021, released a press release about the final analysis for COVAXIN efficacy as part of phase 3 clinical trials after publishing preprint data on medRxiv. Here in this article we are comparing Phase 3 results of world’s 3 most popular COVID vaccines that are in vaccination drives around the world. 2 out of 3 got huge funding from international organizations for R&D and manufacturing and already have won Emergency Use Approval from WHO and FDA but Covaxin has to wait despite its high effectiveness and safety profile because it is from…

G. Baskar*, B. Sangeetha Department of Biotechnology, St. Joseph’s College of Engineering, Chennai – 600119. *Corresponding author email: basg2004@gmail.com Download PDF COVAXIN® is India’s indigenous COVID-19 vaccine developed by Bharat Biotech Company in association with the Indian Council of Medical Research (ICMR) – National Institute of Virology (NIV). The vaccine is developed via Whole-Virion Inactivated Vero Cell technology. Inactivated vaccines fail to replicate and hence they are improbable to revert and root pathological effects. They comprise dead virus, inept of infecting people but still able to inculcate the immune system to escalate a defensive reaction counter to an infection. COVAXIN®…

Millions of fully vaccinated people in India and Africa are confused to land Europe under the EU’s new vaccine passport(Digital Green Certificate) scheme. That’s despite the fact that they all have taken a vaccine that, on the face of it, is already authorized in the EU, as well as by the UK and the WHO. The EU backed up by UK is allowing one brand of the AstraZeneca jab, named Vaxzevria, but its identical, Indian-made version Covishield manufactured under license by India’s Serum Institute, is not one of the vaccines listed for the EU’s new digital travel pass. It means…

Nabanita Roy Chattopadhyay and Tathagata Choudhuri* Department of Biotechnology, Visva-Bharati, Santiniketan. *E-mail: tathagata.choudhuri@visva-bharati.ac.in, Mobile: +919861724726. COVID-19 pandemic, the biggest global issue nowadays, is universally agreed to be won by effective vaccination only, as no conclusive drug and/or treatment strategy is available till date. In comparison to the developed countries like the United Kingdom and the United States of America, the rate of vaccination in India is lower and the percentage of vaccinated persons are much lower. Despite the Central Government’s awareness campaigns and vaccination offers via CoWIN site, this lower rate of vaccination is heightening the risk of the…

The World Health Organization defines vaccine hesitancy as a “delay in acceptance or refusal of safe vaccines despite availability of vaccine services. Vaccine hesitancy has identified as a leading global health threat which has increased in the times of COVID-19. A survey in Israel indicated that the percentage of people who intended to obtain a COVID-19 vaccine was 78% among physicians, 61% among nurses, and 75% in the general population. Low acceptance rates were also observed among Hong Kong nurses in two studies, and in late 2020, only 36% of U.S. HCWs said they were willing to take the vaccine…

by Kamal Pratap Singh Experts from the medical fraternity of India have disapproved Ramdev’s comments about the inefficacy of allopathic medicines in fighting COVID-19. Neither Baba Ramdev nor IMA chief have described which medicine has been the reason of disrespect & deaths. If we talk about of allopathic medicine then Yes they do have failed miserably, not only jeopardized lives as well as the precious money. For COVID-19 Remedisivir, HCQ and several other drugs were granted EUA by FDA/WHO/DCGI and other regulatory agencies which were failed subsequently. Of course there are other allopathic drugs too that are working. As analyzed…

by Rupam Kapoor Department of Botany, University of Delhi, Delhi-110007, India Download PDF Summary At present, agriculture is challenged with meeting the global food demands for the growing population, while maintaining environmental quality and reducing the input of chemical fertilizers and pesticides. In this context, the article gives insights on the beneficial soil microorganisms “arbuscular mycorrhizal fungi” that play key roles in sustainable agriculture and promote plant nutrition and produce safe and high-quality food. Introduction Microbes are ubiquitous tiny organisms that are too small to be seen with the unaided eye. Both plants and animals are closely linked with…